Yes InnerSpace works for EQ2. More Specifically OgreBot or EQ2Bot for InnerSpace works. I've never used OgreBot, but it's supposedly better than EQ2Bot in some aspects. You have to subscribe to lavish software to get InnerSpace, and then also to EQ2Bot separately. I think OgreBot may even be dependent on EQ2Bot, requiring a 3rd subscription if you want to use it, but I could be wrong about that.
However, I used EQ2Bot on some of my EQ2 characters as recently as the end of last year and it worked for the most part. Was able to mostly AFK skill up all of my tradeskills, and it also can afk gather and hunt if you set it up to do so. The hunting part I never got to work all that well though. I say mostly AFK because you have to baby sit it. Sometimes it will mess up, and also it's hard coded for some reason to only allow it to do 10 rush orders before you have to tell it to do 10 more. (Rush orders being the fastest way to skill up, and potentially could make a little cash as well).
Or if you are feeling froggy you can write your own ISX scripts for innerspace to do the stuff.